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For women unable or unwilling to take HRT , several alternatives exist: Fezolinetant : a neurokinin-3 receptor antagonist specifically licensed for moderate to severe vasomotor symptoms, offering a non-hormonal option [19] [20] Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs): medications such as venlafaxine, citalopram, or fluoxetine may reduce hot flash frequency, though efficacy varies

Mawardi, Hani Haytham, et al

Antidepressant use among persons aged 12 and over: United States, 20112014

Therefore, given the diverse functions of Erbin in various signaling pathways, it is suggested that Erbin may play a vital role in clinical disease